The final proposed system of RBC vasodilation within the presence of nitrite would be the reduction of nitrite to NO by Hb. Brooks 1st analyzed the nitrite Hb conversation in 1937 and this do the job was later extended by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to sort metHb and NO (Brooks, 1937; Doyle … Read More